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Grapefruit juice inhibits the metabolism of many medications, including cyclosporine, felodipine, nifedipine, nitrendipine, nisoldipine, carbamazepine, triazolam, and midazolam

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Q: Does Grapefruit juice affect drug metabolism?
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Does orange juice intensify the effects of xanax?

No, the syngergistic effect is exclusive to grapefruit juice. Grapefruit juice is broken down by the same enzyme in the stomach as benzodiazepines, so more of the drug enters your bloodstream if your stomach is "busy" breaking down the grapefruit juice.


What are the negative effects of drinking grapefruit juice?

The negative effects of drinking grapefruit juice include negative interactions with certain drugs, which increase blood levels of the drug to harmful levels. Grapefruit juice inhibits a chemical in the intestine needed to break down many drugs in the body, making the drug become more potent.


Does grapefruit juice affect blood pressure?

It can. Grapefruits and grapefruit juice has been known to alter the metabolism of some medications. Hence: if you are taking blood pressure medicine and ingest grapefruit, the medication may cause some side effects, which can include alerting blood pressure. It is actually like an "enhancer". It can make it seem like you took 5x or more the dose that you originally took. Unfortunately, this can lead to dangerous side affects. Not all people will be affected, as it ineracts with a specific enzyme in your intestines. Talk to your doctor before ingesting grapefruit when on medications.


Is it okay to take Allegra with juice?

WIth most medications, you should take only water. With Zyrtec, you are allowed to take Orange Juice, but you should just take water with it to be safe.


Can you drink grapefruit juice before you take tenormin?

Unlike Calcium Channel Blockers, which effects get enhanced by grapefruit juice, Beta Blockers (Tenormin) absorption from the gut decreases when taken with grapefruit juice. Researchers have found that grapefruit (whole or juice) inhibits certain enzymes in the intestinal mucosa responsible for Tenormin absorption. Therefore it is advised to avoid consuming grapefruit few hours before and after taking Tenormin to assure full absorption of the therapeutic dose of the drug by the gut.


Why cant you eat grapefruit and take lipiture medications?

grapefruit juice interacts with many many drugs... but usually it is only a mild interaction perhaps slightly increasing or decreasing the potency of some medications. but your pharmacist is trained to know these things he is the one to call.


If your taking Lipitor can you eat meat that has been marinated with grapefruit juice?

Grapefruit juice can slow the breakdown of statin drugs in the liver, increasing the risk of drug side effects. But considering the small amount of grapefruit juice that would be left on the meat after marinating and cooking it, there shouldn't be enough to cause any problems. You can ask your pharmacist though, who will be able to give you a more definitive answer.


Can you take accutane and eat grapefruits?

No, you should avoid grapefruit juice because they can cause drug interactions with complications ranging from drowsiness to seizures.


What is the effect of grapefruit juice on drugs?

I'm guessing this is based on the old wives tale that says vitamine c can stop an LSD trip, or sober you up in some way... This theory is completely baseless and untrue, I know of no drug that is affected by grapefruit juice or vitamine c.AnswerGrapefruit juice is processed by your body in the liver by an enzyme which also degrades many drugs (not all drugs, just some such as cholesterol drugs like Lipitor and some blood pressure medications). When taking one of these medications and drinking grapefruit juice, the grapefruit inhibits the metabolism of these drugs (i.e. it is hogging the enzyme all to itself in the liver and not leaving any for the medication so it can't be broken down). The result is having too much of the medication in your body, which can lead to toxicity. Answer:Grapefruit, and grapefruit juice contains several antioxidants that block the enzyme CYP3A4 for roughly 24 hours. This enzyme is responsible for breaking down certain types of drugs. when you take a drug while this enzyme is blocked it might increases the effects of the drugs. Depending on the drug, it can cause reactions that are either minimal, serious, or non existant.


Do diaretics help you pass a drug test for weed?

There are no real drugs or drinks or anything out there that will help you pass a drug test for weed. Beware of scam drinks that say that you'll test clean if you drink it because its a fraud. The only true way to test clean is to well not do it or wait for it to be totally out of your system which for weed is unfortunatly a really long time if you smoke it all the time. There is a way to keep it in your system longer however so stay away from grapefruit juice and anything that has grapefruit juice in it because theres something in grapefruit juice that inhibits or stops the drug from being metabolized. Hope this helps.


Can drinking grapefruit juice make pain pills work better?

yes. although it does so by raising the levels of the drug in your system. so be careful, especially if you are not used to the drug you're taking.


What is in grapefruit that makes it interact with medicines?

A daily glass of grapefruit juice or half of a grapefruit for breakfast is normally considered a healthy diet choice: that grapefruit delivers vitamin C, fiber, and potassium. However, grapefruit can be dangerous if taken along with certain of the statin class of cholesterol-lowering prescription medicines.Grapefruit and grapefruit juice interact with multiple prescription medicines, and consuming grapefruit while on these medications can be dangerous. In fact, there are many medications that interact with grapefruit, including the cholesterol-lowering statins Zocor (simvastatin), Lipitor (atorvastatin) and Pravachol (pravastatin).Which Medications Interact With Grapefruit?Grapefruit should be avoided (or minimized - best bet is to discuss with your doctor) when taking a surprisingly broad group of medicines. According to the FDA's Grapefruit Juice and Medicine May Not Mix, grapefruit can interfere with certain of the cholesterol-lowering statins as listed above, some blood-pressure medications, some antihistamines, as well as other drug classes.How Does Grapefruit Interact With Prescription Medicines?Essentially, the juice of grapefruit changes the absorption of certain drugs into the bloodstream. Katherine Zeratsky, a Mayo Clinic Nutritionist, explains, "Problems arise because chemicals in the fruit can interfere with the enzymes that break down (metabolize) the medication in your digestive system. As a result, the medication may stay in your body for too short or too long a time. A medication that's broken down too quickly won't have time to work. On the other hand, a medication that stays in the body too long can increase to potentially dangerous levels, causing serious side effects." For statins in particular, grapefruit juice increases the level of statin in the blood, to a potentially dangerous level.What If I Take My Prescription Hours After Eating Grapefruit?Though eating grapefruit or drinking grapefruit juice hours before or after taking a prescription medicine seems a good strategy, it is not. Shiew Mei Huang, acting director of the Food and Drug Administration's Office of Clinical Pharmacology, explains, "Drinking grapefruit juice several hours before or several hours after you take your medicine may still be dangerous, so it's best to avoid or limit consuming grapefruit juice or fresh grapefruit when taking certain drugs.ConclusionFor those not on prescription medication of any sort, grapefruit and grapefruit juice are a terrific nutritional choice. But if you take any prescription medication - especially statins to lower cholesterol - you should avoid grapefruit and grapefruit juice, or at least discuss with your doctor.Did You Know?Grapefruit juice decreases the effectiveness of allergy medications like Allegra (fexofenadine) by inhibiting the absorption of the drug itself. It may be less effective with apple and orange juice as well, so the fexofenadine label states "do not take with fruit juices."