granduncle - grandnephews/grandnieces
brother
uncle
None. There is no relation through "my friend"
There is 2 answers your mothers brothers children or your dads sister;"s children
Your dad's brother is your mom's brother-in-law. He is not related to your mom's sister or her children.
They are half brother and sister, they have the same father but different mothers.
Your brother's wife is your children's aunt as long as they are married. If they get divorced, she is no longer any relation to them.
The children are both your cousins[uncle's children]and your nephew and niece[sister's children].
the relation is that person is either your half brother or half sister. 1/2 brother or sisiter
Your mother's sister's children are your 1st cousins.
No relation