Sasuke and Sakura

Answer 1

At the start of the series, Sakura had a deep infatuation for Sasuke Uchiha, rooted primarily in his good looks, cunning, cool attitude, and prodigious talents. For that reason, many of Sakura's early appearances are dedicated to her continuing efforts to win his affection. As the story progresses, she begins to recognize that Sasuke is a real person with imperfections, and develops a more sincere desire to be there for him. Sakura also becomes concerned that Sasuke will someday abandon her and the rest of Konoha in his quest for power. When her fears come true at the end of Part I, Sakura does all that she can to stop Sasuke from leaving, such as professing her love for him and offering to join him. Though touched by her words, they do not stop Sasuke from leaving from Konoha.

Since then, Sakura has made her personal goal to bring Sasuke home, which becomes a recurring component of her role in Part II. Although she still worries about his well-being, Sakura is willing to attack him if it means returning him to Konoha. As time goes on and Sasuke becomes an increasingly more dangerous criminal, Sakura recognizes that Sasuke must be stopped at all costs. She also tells Naruto that she no longer has any feelings for Sasuke since he just keeps breaking her heart. However, Sai and Kakashi suspect that she does still love Sasuke, and that she wants to stop him only so that he does not sink any lower. Upon meeting Sasuke once again, Sakura was shocked and shortly afterwards brought to tears to see how dark he became, and still struggled to whether she could kill Sasuke, giving the international criminal the chance for a first strike. Given a second chance to kill Sasuke, Sakura ultimately realized that she could not do it.

When he was a child, he used to be a very kind boy, loving towards his parents and brother, and respectful to his clansmen and teachers. He was even very proud to being Itachi's brother and Fugaku's son, famous for being devoted protectors of Konoha, and he always desired to emulate them. After Itachi massacred the clan, Sasuke's ideals and personality changed, becoming cold, lonely, cynical, and devoting his entire life to kill Itachi.

When first introduced to Team Kakashi, Sasuke displayed great indifference to his teammates. Feeling superior to all of them, including his teacher, Sasuke was unwilling to cooperate with Naruto Uzumaki or Sakura Haruno, as he felt they would provide him no aid in killing Itachi. However overtime, as he spent more time with his team, Sasuke began to lose some of his anger, caring more about his team than his revenge. To help push him back into his desire for power Orochimaru branded Sasuke with the Cursed Seal of Heaven during the Chūnin Exams to give him a taste of power. Although Kakashi Hatake sealed the Cursed Seal, Sasuke began to draw more power from it in the hopes of getting stronger.

Answer 2

No, how things are happening in this manga, I do not think they will be a Sasuke and Sakura pairing.