Concerning the theme in literature.
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thematically
When something is not relevant, it means that does not pertain to something. For example if you are discussing NASCAR statistics, and your friend is giving you football statistics, they would not be relevant to your discussion.
A relevant component be it for a thing, solution or movement.
The judge decided the prosecution's new evidence was not relevant to the case. Other words that mean relevant are admissible, germane, congruent, and related.
The term "relevant knowledge" means that one would know related information about a topic that is being discussed. That information will also be related to what is being spoken about.