It can be, if the noun "reason" is used to mean the cause or basis for an action.
For example, his justification for running away (his reason for running away) was that he thought he would be mistreated by the police.
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The noun 'reason' is an abstract noun, a word for a cause, explanation, or justification for an action or belief; the power of the mind to think, understand; a word for a concept.The abstract noun form of the verb to reason is the gerund, reasoning.
The definition of the word cited is quote as evidence for or justification of an argument or statement. Another definition for the word cited is mention as an example.
The word reason has a number of definitions. Bearing this in mind, many synonymns are possible; 1. The basis for an act - cause, justification, motive 2. The stated purpose for an action - excuse, explanation, 3. The ability to think - rational, sane, judgement, There are many others. Onecan easily expand on the above list.
Explanation is a noun meaning reason. Synonyms include specification, description, justification, exposition, and commentary. Other synonyms are interpretation and demonstration.
reason...the happening