appendix-supplementary material at the end of a book, article, document, or other text, usually of an explanatory, statistical, or bibliographic nature.
index-(in a nonfiction book, monograph, etc.) a more or less detailed alphabetical listing of names, places, and topics along with the numbers of the pages on which they are mentioned or discussed, usually included in or constituting the back matter.
they are kind of the same, but not exactly.
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The word index is singular. One index. If you have more than one, you can form the plural according to Latin conventions: indices or according to English conventions: indexes. Preference varies from publisher to publisher, and dictionaries differ. Either is correct. Just be consistent within a single document. Also, if you refer to appendix in the plural, you should do it consistently with your treatment of index: that is, appendices or appendixes.
Yes. It is necessary as there may be many appendices such as Appendix A, Appendix B, Appendix C and so on. They need to be enunciated after a ':' mark.
The plural form of appendix is appendices.
Removal of the appendix is called an appendectomy.