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bacterial cell wall synthesis inhibitor

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Q: What is mode of action by cefixime?
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What is better either ciprofloxacin or cefixime for the treatment of urinary tract infections?

Cefixime


Why cefixime and clavulanic acid combination is better than cefixime alone?

Cefixime and Clav- Has practically no rational. Primary because Cefixime is relatively stable against B-lactamase. Hence adding Clav to this combination is a worthless addition.


What are the unique selling point of cefixime?

Cefixime is the most accepted in oral group of cephalosporin.


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Can cefixime 400 BD and azithromycin 1000 OD can be used to treat typhoid?

You can use them. Cefixime for ten days and azithromycin for seven days.


What is the ratio of cefixime and clavulanic acid?

The ratio of cefixime to clavulanic acid in a combination medication is typically 10:1. This means that for every 10 parts of cefixime, there is 1 part of clavulanic acid present in the formulation.


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What is the Best medicine for typhoid?

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What is the composition of antibiotics-zimnic?

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Use of cefixime and clavulanic acid combination?

cefixime and clavulanic acid can be used as a second line therapy where cefixime alone is not able to show it's bacteriocidal activity. Cefixime comes under beta lactum antibiotic category and gets degrade inpresence of beta lactumase enzyme, bacterias have developed resistance against cefixime by producing beta lactamase and ESBLs. Clavulanic acid is an irreversible inhibitor of beta lactamase enzyme and have mild antibiotic activity. when this combination is used, clavulanic acid inhibits beta lactamase enzyme and allow cefixime work as a bacteriocidal. the combination is very useful against cefixime resistant becteria. more research work is required to understand the further use of this combination and also to find out the superiority of this combination over Amoxi+Clav combination.