Yes, the pineal gland secreted increased melatonin at night and it is thought this helps regulate the sleep-wake cycle.
It is commonly used to help with insomnia and jet lag but the results of research studies into this have been disappointing. In one recent study it was helpful in shift workers trying to nap during the day but not in people who had trouble sleeping at night. This may make sense since the level are already high at night so adding more may not matter but taking it during the day is a true change.
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