The half way point from Buffalo New York to Columbus Ohio is around Painesville, Ohio. On I-90 from Buffalo to Cleveland then I-71 South to Columbus takes about 3 hours for each leg (total about 6 hours). There is heavy traffic on these interstates.
Halfway between Columbus and Cincinnati
Cambridge, Ohio is pretty close to halfway.
The halfway point between Columbus, Ohio and Cantonment, Florida is Louisville, Kentucky. The amount of miles that it will take to travel from Columbus, Ohio to Cantonment, Florida is 805.33 miles.
The halfway point between Billings, Montana and Columbus, Ohio falls in Rogers, Minnesota.
Shade Gap, Pennsylvania
Sylva, NC
The city of Berea, Kentucky is halfway between Atlanta, Georgia and Columbus, Ohio.
Ohio is almost 45000 square miles and the halfway point from Cleveland would be different from the halfway point from Cincinnati. Columbus is centrally located. That halfway point is Miami... West Virginia.
The halfway point between Royal Oak, Michigan, and Columbus, Ohio, is North Baltimore, Ohio, between Findlay and Bowling Green on I-75.
Cleveland is closer to Buffalo.
Benezette, Pennsylvania is the halfway point between Long Island, New York and Toledo, Ohio. There is approximately 604 miles between New York and Ohio.
I suppose it would depend on how you go, but Columbus, Ohio would be pretty close to halfway, I would think.