It is used to identify single strains of bacteria therefore, tracing the outbreak of infections.
Phage titration is needed to determine the concentration or titer of phages in a sample, which is crucial for ensuring the effectiveness of phage-based therapies, determining the optimal phage concentration for experiments, and monitoring phage growth dynamics in culture. Titration allows researchers to quantify the number of active phages present in a sample, providing valuable information for various applications in phage research and biotechnology.
Phage viruses specifically infect bacteria and have no capability to infect human cells. In fact, phage therapy is being explored as a potential treatment for bacterial infections in humans.
phage
temperate phage
DNA single
The substance a phage leaves outside its host cell is typically referred to as the "phage progeny" or "phage particles." These particles can include newly synthesized phage DNA and proteins, as well as the phage capsid that encapsulates the genetic material. This material can go on to infect other host cells and continue the phage replication cycle.
Temperate phage superinfection immunity is a phenomenon where a cell harboring a lysogenic phage becomes immune to subsequent infection by the same or a related phage due to the presence of the resident prophage. This immunity is conferred by the repressor protein produced by the resident prophage, which prevents the incoming phage from entering lytic cycle and instead integrates into the host genome as a prophage.
Bacillus anthracis is susceptible to gamma phage because the phage has evolved to target and infect specific receptors on the surface of the bacterium. This interaction enables the gamma phage to inject its genetic material into the bacterium, hijacking its machinery to produce more phage particles and ultimately leading to the destruction of the bacterial cell.
When a phage attaches to a bacterium, it injects its genetic material (DNA or RNA) into the cell. The phage capsid (outer protein coat) typically stays attached to the cell surface during this process.
A phage injects its genetic material (DNA or RNA) into the bacterium when it attaches to it. This genetic material then hijacks the bacterium's machinery to replicate itself, eventually leading to the destruction of the bacterium.
The cast of Phage - 1997 includes: Jasper Bagg as Burke