Danzo and the Konoha Council ordered him to wipe out the Uchiha Clan, who were planning a coup d'etat against Konoha. He made a deal with Madara Uchiha, who would spare Konoha if Itachi would help him wipe out the Uchiha Clan, who had betrayed Madara earlier. Madara agreed and the two wiped out the entire Uchiha Clan in one night. (With the exception of themselves and Sasuke Uchiha, Itachi's younger brother due to the fact that Itachi could not bring himself to kill his little brother.)
Suaskes (?) If you're talking about Naruto, Sasukes parents actually get killed by Itachi (Sasukes older brother)
Fugaku and Mikoto Uchiha
yes itachi killed them
sai is a foundation member who works for danzo currently sai is in team kakashi, and sai did not try to kill naruto he was testing his strength according to sai
To kill Uchiha Itachi, his older and hotter bro
Itachi and great thought sasuke tries to kill him from episode 1
No
When Itachi said to Sasuke to kill his closest friend, he meant that when a member of their clan does that, their sharingan develops in a special way, therefore giving them more power.
sai told sakura naruto loved her then shikamaru told sakura that he and the others were going to kill saskue because hes a criminal and almost started a war
No cane did not kill his parents.
He doesn't have one.
Really good!