Tacos are tortillas with various different fillings. Even the tortilla is a complex mixture of substances such as starch, water and proteins, and as for the filling, it depends what you put in it!
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Tacos are typically made with a corn or wheat tortilla that is filled with a variety of ingredients such as meat (like beef, chicken, or fish), vegetables, cheese, salsa, and other toppings like guacamole or sour cream.
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A substance that dissolves in another substance is called a solute.
The possessive form of substance is "substance's".
Substance can function as a noun.
A solute can dissolve in another substance. The substance that does the dissolving is called the solvent.