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One of the only ways is to make use of nucleophilic aromatic substitution (SN_Ar). Add a nitro group para to the OH, attack the OH carbon with 1 eq. ammonia, work it up with another eq., convert NH2 to a diazonium salt with NaNO2 + HCl @ 0~4 degrees C, then remove it with H3PO2.

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βˆ™ 5mo ago

Phenol is converted to aniline via the Zinin reduction reaction, which involves the reaction of phenol with ammonia and sodium metal. The phenol first forms a sodium phenoxide intermediate, which reacts with ammonia to give an amine salt. Finally, the amine salt is then reduced by sodium metal to produce aniline.

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mecanism of sulfanilic asid

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Q: What is the reaction mechanism of phenol into aniline?
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Why is it that aniline has a high boiling point to phenol and phenol has a high boiling point than toluene and toluene has a high boiling point than benzene?

Aniline has a higher boiling point than phenol because aniline can form strong hydrogen bonds due to the presence of an amino group. Phenol has a higher boiling point than toluene because phenol molecules can form intermolecular hydrogen bonds because of the hydroxyl group. Toluene has a higher boiling point than benzene due to the presence of a bulky methyl group which increases Van der Waals forces between toluene molecules.


What is the equation for the reaction of aniline with acetic anhydride?

The reaction of aniline with acetic anhydride typically forms the product N-phenylacetamide and acetic acid. The chemical equation for the reaction can be represented as: C6H5NH2 + (CH3CO)2O β†’ C6H5NHC(O)CH3 + CH3COOH.


What is the name of C6H5COOC2H5?

The formula is for benzyl acetate (as an example).


What happens in the reaction between phenol and sodium hydroxide?

In the reaction between phenol and sodium hydroxide, the phenol is deprotonated by the base, forming the phenolate ion. This reaction is an acid-base reaction where phenol acts as an acid and donates a proton to form water. The products of the reaction are the phenolate ion and water.


What type of reaction between phenol and potassium permanganate?

Phenol reacts with potassium permanganate in an acidic medium to form benzoquinone as the main product, along with small amounts of hydroquinone. This reaction is a redox reaction where phenol is oxidized to form benzoquinone.

Related questions

How to convert aniline to picric acid?

React aniline with HCl/NaNO2 (diazotisation) followed by reaction with KOH to give phenol. Nitration of phenol with fuming nitric acid gives picric acid (or trinitrophenol).


In lederer manasse reaction phenol is converted into?

In the Leuckart-Wallach reaction, phenol is converted into aniline through the reduction of the nitro group, followed by acid hydrolysis.


Why is o-aniline phenol less soluble in water than m-aniline phenol?

In o-aniline phenol Intramolecular hydrogen bonding occurs which is not possible in meta and is responsible for less solubility


In Reimer Tiemann reaction of phenol with CCl4 to from the trichloromethane derivative what is the electrophile or the mechanism?

In the Reimer-Tiemann reaction, the electrophile is the carbene (CHCl3) that forms from the reaction of phenol with CCl4 in the presence of a base such as NaOH. This carbene then reacts with phenol to form the trichloromethane derivative. The mechanism involves the generation of the carbene intermediate, which attacks the phenol molecule to form the final product.


Why is it that aniline has a high boiling point to phenol and phenol has a high boiling point than toluene and toluene has a high boiling point than benzene?

Aniline has a higher boiling point than phenol because aniline can form strong hydrogen bonds due to the presence of an amino group. Phenol has a higher boiling point than toluene because phenol molecules can form intermolecular hydrogen bonds because of the hydroxyl group. Toluene has a higher boiling point than benzene due to the presence of a bulky methyl group which increases Van der Waals forces between toluene molecules.


What is the product of a reaction between bromine and aniline in non polar solvent?

The product of a reaction between bromine and aniline in a non-polar solvent is typically the bromination of aniline, where bromine substitutes a hydrogen atom on the benzene ring of aniline to form bromoaniline. This reaction is an electrophilic aromatic substitution reaction.


What is the equation for the reaction of aniline with acetic anhydride?

The reaction of aniline with acetic anhydride typically forms the product N-phenylacetamide and acetic acid. The chemical equation for the reaction can be represented as: C6H5NH2 + (CH3CO)2O β†’ C6H5NHC(O)CH3 + CH3COOH.


What is the reaction of phenol with phosphorus pentachloride?

Phenol reacts with phosphorus pentachloride to form chlorobenzene and phosphoric acid as byproduct. The reaction involves substitution of the hydroxyl group in phenol with a chlorine atom.


What is the reaction product for bromine plus phenol?

The reaction product of bromine and phenol is 2,4,6-tribromophenol. In this reaction, the bromine replaces the hydrogen atoms on the phenol ring to form a tribrominated product.


Balanced equation for the reaction of phenol and sodium carbonate?

The balanced chemical equation for the reaction of phenol (C6H5OH) with sodium carbonate (Na2CO3) is: 2C6H5OH + Na2CO3 β†’ 2C6H5ONa + H2O + CO2


What is the reaction of benzoyl chloride with aniline?

Benzoyl chloride reacts with aniline to form N-phenylbenzamide. In the reaction, the chlorine atom of benzoyl chloride is replaced by the amino group of aniline. The reaction is often carried out in the presence of a base to help neutralize the hydrogen chloride byproduct.


What is the name of C6H5COOC2H5?

The formula is for benzyl acetate (as an example).