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Coc-H+Cl− + NaHCO3 → Coc + H2O + CO2 + NaCl= Crack (Freebase) Cocaine

When sodium bicarbonate is heated, it breaks down into carbon dioxide and sodium carbonate. The cocaine molecule contains hydrochloride, which the sodium carbonate reacts to. The reaction strips the cocaine molecule of the hydrochloride, which leaves it as an oily free base, which can be molded into a rock-like shape.

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14y ago
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6mo ago

When cocaine hydrochloride is heated with sodium bicarbonate, it undergoes a chemical reaction known as a base-catalyzed transesterification. This reaction converts the cocaine hydrochloride into its freebase form, known as crack cocaine, which is then vaporized and inhaled for its psychoactive effects.

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Q: What is the chemical reaction between cocaine hydrochloride and sodium bicarbonate?
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