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Spherocytes are abnormally shaped red blood cells that appear more round and compact than their normal biconcave disc shape. They can result from conditions like autoimmune hemolytic anemia, hereditary spherocytosis, or certain infections. Spherocytes have increased fragility and decreased flexibility, which may lead to their premature destruction and contribute to anemia.

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Q: What is spherocytes?
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What are spherocytes?

Spherocytes are abnormally round red blood cells that lack the central pallor seen in normal red blood cells. They are often associated with certain medical conditions such as autoimmune hemolytic anemia. Spherocytes are more fragile than normal red blood cells and may be removed from circulation more rapidly, leading to hemolytic anemia.


What does a low MCHC count mean-31.7?

bordeline of macrocytic anemia, which could be a folic acid deficiency, liver disease, hereditary spherocytes or B-12 deficiency


When comparing blood smears of patient with intact spleens and those of patients without spleens the blood smears of patients without spleens will likely reveal what?

Blood smears of patients without spleens are likely to show Howell-Jolly bodies, which are nuclear remnants normally removed by the spleen. Additionally, there may be an increase in target cells and spherocytes due to altered red blood cell morphology. This can be a diagnostic indicator of asplenia.


What four properties of blood affect the esr?

The four properties of blood that affect the ESR (erythrocyte sedimentation rate) are the concentration of fibrinogen, the size and shape of red blood cells, the presence of inflammatory proteins, and the presence of abnormal proteins like sickle cells or spherocytes. These properties can impact the rate at which red blood cells settle in a tube, affecting the ESR measurement.


What does that mean if you MCH test is high?

A high mean corpuscular hemoglobin (MCH) level could indicate conditions like macrocytic anemia, liver disease, or a vitamin B12 or folate deficiency. Further evaluation and testing by a healthcare provider are needed to determine the underlying cause.


Nursing responsibilities for patient before and after Complete blood count?

Pretest:Positively identify the patient using at least two unique identifiers before providing care, treatment, or services.Patient Teaching:Inform the patient this test can assist in evaluating the amount of hemoglobin in the blood to assist in diagnosis and monitor therapy.Obtain a history of the patient's complaints, including a list of known allergens, especially allergies or sensitivities to latex.Obtain a history of the patient's cardiovascular, gastrointestinal, hematopoietic, hepatobiliary, immune, and respiratory systems; symptoms; and results of previously performed laboratory tests and diagnostic and surgical procedures.Note any recent procedures that can interfere with test results.Obtain a list of the patient's current medications, including herbs, nutritional supplements, and nutraceuticalsReview the procedure with the patient. Inform the patient that specimen collection takes approximately 5 to 10 min. Address concerns about pain and explain that there may be some discomfort during the venipuncture.Sensitivity to social and cultural issues, as well as concern for modesty, is important in providing psychological support before, during, and after the procedure.There are no food, fluid, or medication restrictions unless by medical direction.Intratest:If the patient has a history of allergic reaction to latex, avoid the use of equipment containing latex.Instruct the patient to cooperate fully and to follow directions. Direct the patient to breathe normally and to avoid unnecessary movement.Observe standard precautions, and follow the general guidelines. Positively identify the patient, and label the appropriate tubes with the corresponding patient demographics, date, and time of collection. Perform a venipuncture; collect the specimen in a 5-mL lavender-top (EDTA) tube. An EDTA Microtainer sample may be obtained from infants, children, and adults for whom venipuncture may not be feasible. The specimen should be mixed gently by inverting the tube 10 times. The specimen should be analyzed within 24 hr when stored at room temperature or within 48 hr if stored at refrigerated temperature. If it is anticipated the specimen will not be analyzed within 24 hr, two blood smears should be made immediately after the venipuncture and submitted with the blood sample. Smears made from specimens older than 24 hr may contain an unacceptable number of misleading artifactual abnormalities of the RBCs, such as echinocytes and spherocytes, as well as necrobiotic white blood cells.Remove the needle and apply direct pressure with dry gauze to stop bleeding. Observe/assess venipuncture site for bleeding or hematoma formation and secure gauze with adhesive bandage.Promptly transport the specimen to the laboratory for processing and analysis.Post-test:A report of the results will be sent to the requesting HCP, who will discuss the results with the patient.Depending on the results of this procedure, additional testing may be performed to evaluate or monitor progression of the disease process and determine the need for a change in therapy. Evaluate test results in relation to the patient's symptoms and other tests performed.


Blood smear?

A blood smear is a laboratory test where a drop of blood is spread thinly on a glass slide and stained to allow for the visualization of blood cells under a microscope. It is used to assess the morphology of different types of blood cells, such as red blood cells, white blood cells, and platelets. Abnormalities in the appearance or distribution of these cells can provide valuable diagnostic information for various medical conditions.