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The boat conformation of cyclohexane is significant because it allows for the positioning of axial and equatorial substituents in a way that minimizes steric hindrance. Axial substituents are positioned vertically, while equatorial substituents are positioned horizontally, reducing the strain on the molecule and increasing stability.

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Q: What is the significance of the boat conformation in terms of the positioning of axial and equatorial substituents in cyclohexane?
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