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A good eluent is one that gives good separation between your target compound and impurities. Use a TLC plate to get a feel for the effect of the eluent on your purification. If this is your first time purifying this reaction, a good Rf to aim for in regard to your target compound is 0.2 - 0.25, and impurities should have at least an Rf difference of 0.1 - 0.15 compared to your target compound. Benzene is rather toxic and should not be used for eluting large quantities of compound. But if your reaction is around 2g scale or less, benzene should be ok.

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βˆ™ 15y ago
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βˆ™ 5mo ago

Yes, benzene and chloroform can be used as an eluent in chromatography for certain applications. These solvents have different polarities and can help separate compounds with varying polarities. However, chloroform is toxic and poses health risks, so it should be used with caution in a laboratory setting.

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Q: Is benzene and chloroform mixture a good eluent?
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What are good solvents for lipids?

Common solvents for lipids include chloroform, methanol, and a mixture of chloroform/methanol. These solvents can effectively dissolve a wide range of lipids for various analytical techniques such as extraction, chromatography, and mass spectrometry. Remember to handle these solvents with caution as they can be flammable and toxic.


What properties does benzene have to make it good to use?

Convert the benzene into Phenol which is a good antiseptic material.


Will butter dissolve in chloroform?

No, butter will not dissolve in chloroform because chloroform is not a good solvent for non-polar compounds like fats and oils. Butter is mostly composed of fat and water, neither of which are soluble in chloroform.


Does Benzene and water form a good solution?

No benzene is extremely hydrophobic and sits like an oil on top of the water.


What is the conductivity of chloroform?

The conductivity of chloroform is very low, as it is a nonpolar solvent and does not dissociate into ions in solution. Therefore, chloroform is not a good conductor of electricity.


Is benzene a metal?

No, benzene is not a metal. Benzene is a colorless liquid hydrocarbon compound classified as an organic compound. Metals are elements that typically have a shiny appearance, good electrical and thermal conductivity, and can form positive ions by losing electrons. Benzene does not exhibit these properties.


Is grease soluble in benzine?

Yes, grease is soluble in benzene as benzene is a good solvent for grease and can dissolve its non-polar components.


What will happen with the heated iodine if it will be mix with the chloroform?

Not something good. Lol.


How can Chloroform be bad and good for you?

Chloroform can be harmful if inhaled, ingested, or absorbed through the skin, as it can cause dizziness, nausea, and potentially damage the liver and kidneys. However, chloroform does have some medical uses, such as in anesthesia and as a solvent in the laboratory when used under controlled conditions.


What dissolves polycaprolactone?

Polycaprolactone can be dissolved in a variety of common solvents, including acetone, chloroform, ethanol, methylene chloride, and ethyl acetate. Heating the solvent and stirring can help facilitate the dissolution process.


Is chloroform aprotic?

Yes, chloroform is an aprotic solvent. Aprotic solvents do not have any active hydrogen atoms that can participate in hydrogen bonding or proton transfer reactions. Chloroform's lack of active hydrogen atoms makes it a good solvent for reactions that are sensitive to the presence of protic solvents.


Is benzene in benzodiazepines?

No, benzene is not present in benzodiazepines. Benzodiazepines are a class of psychoactive drugs that contain a benzene ring in their molecular structure, but the actual compound benzene is not present in these medications.