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Why does hyperpolarization cause a spike in neuronal activity?

Kyleigh Kling ∙

Lvl 10

∙ 2mo ago

Updated: 2/6/2025

Hyperpolarization causes a spike in neuronal activity because it increases the difference in electrical charge between the inside and outside of the neuron, making it more likely for the neuron to generate an action potential and transmit signals.

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∙ 2mo ago

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Q: Why does hyperpolarization cause a spike in neuronal activity?

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Hyperpolarization causes a spike to occur because it increases the difference in electrical charge between the inside and outside of a neuron, making it more likely for the neuron to generate an action potential or spike.

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Why does hyperpolarization cause a spike to occur?

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The inter-spike interval is the time between consecutive action potentials. The frequency of action potentials is inversely related to the inter-spike interval, meaning shorter inter-spike intervals result in higher action potential frequencies. This relationship is crucial in determining the rate of neuronal firing.

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