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The official definition for anti streptolysin is " the antibody made against streptolysin O, an immunogenic, oxygen-labile hemolytic toxin produced by most strains of group A and many strains of groups C and G streptococci."
Streptolysin is a hemolytic toxin produced by certain strains of bacteria, particularly Streptococcus pyogenes. It causes destruction of red blood cells, leading to hemolysis and release of hemoglobin. Streptolysin can contribute to the pathogenicity of the bacteria by allowing them to evade host immune responses and spread within the body.
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What is anti streptolysin?
The official definition for anti streptolysin is " the antibody made against streptolysin O, an immunogenic, oxygen-labile hemolytic toxin produced by most strains of group A and many strains of groups C and G streptococci."
What is an antistreptolysin?
An antistreptolysin is an antibody made against streptolysin.
Does streptococcus pyogenes produce exotoxin?
Yes, Streptococcus pyogenes can produce exotoxins such as streptolysin O and streptolysin S, which contribute to its pathogenicity. These exotoxins can damage cell membranes and contribute to tissue destruction during infections.
What is the Treatment for a high aso titer?
This is a serologic test, known as anti-streptolysin O. It measures the quantity of antibody to a component of streptococcal bacteria. This test is useful in diagnosing scarlet fever, rheumatic fever and other streptococcal disease. Treatment would depend on which particular malady needs to be dealt with.
In which conditions is ASO titer raised?
ASO (Anti-streptolysin O) titers are raised in conditions such as streptococcal infections, rheumatic fever, and post-streptococcal glomerulonephritis. These conditions are typically associated with an immune response to Group A Streptococcus bacteria.
What are exoenzymes from pathogens?
Exoenzymes are digestive enzymes that are secreted by the pathogen into the surrounding tissues, allowing the pathogen to further invade the host's tissues. For example, Streptococcus pyogenes secretes streptokinase to dissolve blood clots, allowing wound invasion, and streptolysin, which digests red blood cells and other body cells. Clostridium perfringens, an agent of gangrene, secretes a lipase that damages cell membranes, creating more dead tissue for these bacteria to invade.
Your aso titer level is 400 iul and your age was 29 yrs is this a serious problem in future and what care should you take?
When the body is infected with the bacteria streptococci, it produces antibodies to combat the various antigens that the streptococci will produce. One such antibody is the anti-streptolysin O or ASO to attack the antigen streptolysin O whose main purpose is to break open the red blood cells to cause hemolysis. The ASO titer test can determine a raised or rising level of ASO which can indicate a past or present infection, and a normal level value is around 200 units. When ASO levels are high, chances are the individual is infected with streptococcus which is signaled by a soar throat leading to more serious conditions such as rheumatic fever, scarlet fever, and disorder of the kidneys. Steps to take to prevent streptococci infections are; avoid people with soar throats or known to have strep throats, wash hands frequently after using items which may harbor the bacteria, don't share food or drinks with a sick individual.
What r bacterial aggressins?
Bacterial aggressins are virulence factors produced by some bacteria that can damage host tissues and promote infection. They may include toxins, enzymes, adhesins, or other molecules that help the bacteria evade the host immune system and establish infection. Aggressins play a key role in the pathogenicity of certain bacteria.
What is serology in immunology?
Serology (ser -> serum; ology -> study of) is the set of experiments and tests that can be done using serum. Serum is the non-cellular component of blood. That is, it's the liquid (with all its lipids and proteins) that is left over after all the red and white blood cells have been removed. Serology could involve the measurement of antibody titers (amounts) or cytokine concentrations.
Antistreptolysin O titer?
The antistreptolysin O titer is a blood test used to detect the presence of antibodies against the streptolysin O toxin produced by Group A Streptococcus bacteria. Elevated titers can indicate a recent or current infection with these bacteria, particularly in cases of streptococcal infections such as strep throat or rheumatic fever.
What are the probable causes of rheumatic disorders?
In such large population of people, there are going to be few patients, whose immune system is defective. and they produce antibody against there own proteins. But immunity is normally very precise in nature and will not produce antibody against self body proteins. You have got one such example of immune response in case of Rheumatic fever. Patient gets an attack of beta haemolyticus infection in throat. After 3 weeks patient come to you with swollen joints, raised E.S.R. and raised 'anti streptolysin O' titre. In almost 100 % of such patients you get the streptococci recovered from his throat. Indicting chronic infection. So in case of Rheumatiod arhtritis, ankylosing spondilitis or other rheumatic conditions also, you may have a bacterial infection responsible for the same. You can not culture 'all' the bacteria and so the relation is not established. So many patients coming with rheumatic joints respond well to removal of infected tooth. With in 3 weeks E.S.R. is settled and joints pain disappear. You may have chronic pelvic inflammatory disease in case of females. Which is very common and multiple organisms may be involved in it. As fallopian tubes are exposed to the exterior. This is so common that you consider 20 mm/hour E.S.R. as normal in case of females as against 10 mm/ hour in case of males. You may have ingrowing toe nails, a sebaceous cyst, chronic otitis media, chronic sinusitis, hepatitis B infection, sub diaphragmatic abscess healed tuberculous lesion, leprosy, fungal infection of nails. In one patient V.D.R.L. was positive and responded well to oral penicillin tablets for three weeks, who could not walk, due to swollen joints. Experts may identify more area of chronic infections. Only thing that infection should be 'inside' the body so that body take it offensively. Obviously intestinal worm infestations are not 'inside' the body. This is not a new concept and was there in 1970's, when medical teachers used to find the infective focus and treat the same. This concept is lost in the era of super-specialisation. Probably almost all autoimmune disorders are caused by microbial infections or the worm infestations situated inside the body like billalziasis.
What are the example of selective media?
Examples of selective media include MacConkey agar, Eosin methylene blue agar, and Mannitol salt agar. These types of media contain ingredients that selectively inhibit the growth of certain organisms while allowing the growth of others.
