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Pili are thin, hair-like projections on the surface of organisms such as bacteria. The pyelonephritis-associated pili, or PAP, of uropathogenic E. coli (which is the major cause of urinary tract infections) are homologous to type I pili, which is composed of pilin subunits and binds to mannose residues on host cell surfaces. PAP, however, are more thin and flexible and bind to the human receptor GBO4.

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15y ago
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5mo ago

Pyelonephritis-associated pili are hair-like appendages on the surface of certain bacteria that help them adhere to the cells of the kidney. These pili play a crucial role in the development of pyelonephritis, a kidney infection often caused by bacteria like Escherichia coli.

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