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What is bioisoterism?

Updated: 6/18/2024

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∙ 13y ago

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Bioisosterism is a concept in medicinal chemistry where atoms or groups in a molecule are replaced with other atoms or groups to maintain similar biological activity. The aim is to improve properties such as solubility, stability, or selectivity of a drug while maintaining its pharmacological effects. This approach can help in the design of new drugs with improved characteristics.

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