It appears there may be a spelling error in your question. The correct term is "chromosomes," which are thread-like structures found in the nucleus of cells that carry genetic information. Chromosomes are made up of DNA and proteins and are essential for cell division and the transmission of genetic traits from one generation to the next.
Giving DNA can be required by law enforcement as part of a criminal investigation, through a court order, or voluntarily in some genetic testing scenarios. Privacy and consent should always be considered when DNA is being collected.
a "normal" human being should have a total of 46 chromosomes. 23 from mom, 23 from dad. if something goes wrong during meiosis, the chromosomes may not be separated normally and a gamete (sex cell, known as sperm or egg) will have either too few or too many chromosomes. this is known as aneuploidy. the effects of aneuploidy on the zygote will vary depending on what chromosomes you are talking about. in the case of chromosome #21, having one extra is called "trisomy 21" which leads to the condition known as down syndrome. chromosome pairs 1-22 are a person's autosomes. the 23rd pair are sex chromosomes. aneuploidy affecting the sex chromosomes can have various effects, depending on what chromosomes are inherited. as you can see, the effects of aneuploidy depend on the specific chromosome number/pair. aneuploidy usually is not fatal.