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What is the difference between the Kozak sequence and the Shine-Dalgarno sequence in terms of their roles in translation initiation?

Susanna Doyle ∙

Lvl 10

∙ 1mo ago

Updated: 2/6/2025

The Kozak sequence is found in eukaryotic mRNA and helps the ribosome to identify the start codon for translation initiation. The Shine-Dalgarno sequence is found in prokaryotic mRNA and helps the ribosome to bind to the mRNA and start translation. Both sequences play important roles in translation initiation, but they are specific to different types of organisms.

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Q: What is the difference between the Kozak sequence and the Shine-Dalgarno sequence in terms of their roles in translation initiation?

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What are the differences between the Shine-Dalgarno sequence and the Kozak sequence in terms of their roles in translation initiation?

The Shine-Dalgarno sequence is found in prokaryotic mRNA and helps ribosomes bind to the mRNA to start translation. The Kozak sequence is found in eukaryotic mRNA and helps ribosomes identify the start codon for translation initiation. Both sequences play important roles in translation initiation, but they are specific to different types of organisms.

How does the eukaryotic initiation complex locate the true start codon?

The eukaryotic initiation complex locates the true start codon by scanning the mRNA molecule from the 5' cap, aided by initiation factors. The complex recognizes the start codon (usually AUG) in a favorable sequence context and assembles around it to initiate translation.

Translation begins when the initiator tRNA binds to the?

start codon on the mRNA strand. This signals the ribosome to begin assembling the amino acid sequence based on the mRNA instructions.

Why methionine is removed from protein in post translation modification?

Methionine is removed from a protein during post-translation modification because it acts as the start codon during the translation process, ensuring proper initiation of protein synthesis. Once the protein is made, this initial methionine can be cleaved off to reveal the true N-terminus of the protein. This modification helps with protein function, localization, and stability.

What is the difference between succeeding terms called?

The difference between succeeding terms in a sequence is called the common difference in an arithmetic sequence, and the common ratio in a geometric sequence.

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Related Questions

What are the differences between the Shine-Dalgarno sequence and the Kozak sequence in terms of their roles in translation initiation?

The Shine-Dalgarno sequence is found in prokaryotic mRNA and helps ribosomes bind to the mRNA to start translation. The Kozak sequence is found in eukaryotic mRNA and helps ribosomes identify the start codon for translation initiation. Both sequences play important roles in translation initiation, but they are specific to different types of organisms.

Difference between kozak sequence and Shine-Dalgarno sequence?

The Kozak sequence is a short sequence surrounding the start codon in eukaryotic mRNA that helps in the initiation of translation. The Shine-Dalgarno sequence is a purine-rich sequence in bacterial mRNA that helps in ribosome binding and initiation of translation by base pairing with the 16S rRNA in the small ribosomal subunit. Both sequences play crucial roles in initiating protein synthesis in their respective organisms.

How does the eukaryotic initiation complex locate the true start codon?

The eukaryotic initiation complex locates the true start codon by scanning the mRNA molecule from the 5' cap, aided by initiation factors. The complex recognizes the start codon (usually AUG) in a favorable sequence context and assembles around it to initiate translation.

Translation begins when the initiator tRNA binds to the?

start codon on the mRNA strand. This signals the ribosome to begin assembling the amino acid sequence based on the mRNA instructions.

Why methionine is removed from protein in post translation modification?

Methionine is removed from a protein during post-translation modification because it acts as the start codon during the translation process, ensuring proper initiation of protein synthesis. Once the protein is made, this initial methionine can be cleaved off to reveal the true N-terminus of the protein. This modification helps with protein function, localization, and stability.

How is the protein produced by translating the mRNA into its amino acid sequence?

Translation

What event in transcription initiation likely occurs last?

The binding of RNA polymerase to the promoter sequence is the likely event that occurs last in transcription initiation. This binding allows for the initiation of RNA synthesis and the subsequent elongation of the RNA molecule.

What is the difference between the terminator sequence and the stop codon in genetic transcription and translation processes?

The terminator sequence marks the end of a gene during transcription, signaling the RNA polymerase to stop. The stop codon, on the other hand, signals the end of protein synthesis during translation, causing the ribosome to release the completed protein.

Translation is initiated at which codon sequence?

AUG-Methionine

What is the difference between succeeding terms called?

The difference between succeeding terms in a sequence is called the common difference in an arithmetic sequence, and the common ratio in a geometric sequence.

What is the base sequence for the mRNA start codon?

The base sequence for the mRNA start codon is AUG. It codes for the amino acid methionine and signals the initiation of protein synthesis.

What is a sequence in which a common difference separates terms?

arithmetic sequence

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