It is 275 miles via CA-88 and CA-49.
Reno is about 200 miles away from Yosemite Valley. You would have to take Tioga Road to the north of the valley.
The driving distance from Knoxville, Tennessee to Reno, Nevada is 2,327 miles.
About 150 road miles.
The driving distance from Dallas, TX to Reno, NV is 1,664 miles.
The driving distance from Reno-Tahoe International Airport to Lake Tahoe is 59 miles.
It is 275 miles via CA-88 West and CA-49 South with an estimated driving time of 6 hours and 6 minutes according to Google Maps.
The driving distance from Orange County, CA, USA to Reno, NV, USA is 552.87mi / 889.77km
The driving distance from LAX to Reno, NV is 524 miles.
The driving distance from Reno, NV, USA to Twin Falls, ID, USA is 453.76mi / 730.25km
523 miles
The driving distance is about 2,280 road miles.