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  1. Take I-81 SOUTH to I-77 SOUTH to Charlotte, NC at EXIT 81 in Virginia.
  2. Take I-77 SOUTH through Virginia and North Carolina (go thru Charlotte) to I-26 EAST (TO I-95) to CHARLESTON at END I-77 in Columbia, South Carolina.
  3. Take I-26 EAST to I-95 SOUTH to SAVANNAH at EXIT 169A.
  4. Take I-95 SOUTH to I-295 SOUTH at EXIT 362B in north Jacksonville, Florida.
  5. Take I-295 around Jacksonville to I-10 WEST to LAKE CITY at EXIT 21B.
  6. Take I-10 WEST to I-75 SOUTH to TAMPA at EXIT 296A in Lake City.
  7. Take I-75 SOUTH to Sarasota.
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Q: What is best route to drive Syacuse NY to Sarasota Fl?
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