About 2.5 hours on the US Interstate Highway system.
100 miles
I-75 is 1786 miles long. At an average 60 mph, it would take 29 hours, 46 minutes.
The distance from Jekyll Island, Georgia to Savannah is 93.1 miles. The drive would take about an hour and a half on Interstate 95.
If you traveled on Interstate 76W and Interstate 80W from Philadelphia PA to Denver CO the 1745 miles would take you 26 hours. If you took Interstate 76W and Interstate 80W from Philadelphia PA to Denver CO the 1745 miles would take you 26 hours traveling an average of 67 mph.
Obviously that depends on how fast you drive and how often you stop. If most of the way is Interstate, it would take me around 14 hours.
The drive is 383 miles, with a drive time of about 6 hours, assuming you take the Interstate (I-5) rather than the coast highway.
285 miles.
Interstate 40 is 2,555.10 miles long. The only two interstates in the United States that are longer than Interstate 40 are I-80 and I-90.
That depends on the speed limit. At 60 mph, it would take 45/60 = .75 hours , or 45 minutes ( a mile per minute)
It is about a 6 hour drive. The trip is over 380 miles long. Most of the trip is along Interstate 5.
Interstate 10 is approximately 2,460 miles long, stretching from Santa Monica, California to Jacksonville, Florida.