It depends on the speed at which you drive.
4
as long as it takes
About 3 hours for the 180 mile drive.
Assuming you mean Orlando, FL the answer is about 11hours.
About 53 minutes
Check Mapquest.com
About a three hour drive on the highways.
12 hours
19
235 miles
The drive from Orlando to Jacksonville via I-4 and I-95 is approximately 2.5 hours.