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A pulmonary embolism is a tissue fragment (part of a blood clot, fat, amniotic fluid, part of a tumour or bullet fragment) that became loose in the blood stream and was carried by the blood stream to a different location. A pulmonary embolism is, in most cases, a thromboembolism (part of a blood clot), which is carried from the deep veins of the legs or the pevis. It travels up the blood stream, through the inferior vena cava, into the heart, and subsequently into the pulmonary artery. In the pulmonary artery, it arrests, forming a potentially life threating occlusion.

Cor pulmonale is hypertrophy of the right ventricle due to chronic pulmonary hypertension. The pulmonay hypertension means that the right ventricle has to pump blood with greater force, causing its muscle to hypertrophy (enlarge in size).

Therefore, to summarize, a pulmonary embolism is an obstruction of pulmonary blood flow while cor pulmonale is the morphological change of the right ventricle due to pulmonary hypertension.

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Q: What is the difference between cor pulmonale and pulmonary embolism?
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