The earliest attempts to abolish slavery were the abolitionist movements that started in the 1750s. This proved unsuccessful because people did not want to give up their slaves and laughed at the idea. This continued to be unsuccessful because Thomas Jefferson, the owner of slaves himself, didn't wish to include provisions in the Constitution.
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The first American colony to abolish slavery was Vermont. Vermont abolished slavery in 1777 and after this the abolish movement spread.
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William Wilberforth?
The 13th Amendment.
The abolitionists.