With multiple misfires originating from the same coil pack, my guess would be to replace the driver's side coil pack.
not real
2001 ford f 150 misfire on acceleration
You have bad spark plugs and or cap and rotor
In theory, it could, but in all practicality, it would not. The four main causes of misfires are faulty sparkplugs, bad spark plug wires, bad fuel injectors or a loss of compression.
Could be a bad coil (each cylinder has its own) common problem
the injectors....
Defective spark plug or plug wire. Can also be blown head gasket or burnt valve.
Check your coil pack for cracks and try spraying it with a water repellent such as WD-40.
Engine misfires. P0300 corresponds to misfires that are random among all cylinders, whereas P0301-P0306 correspond to specific cylinders. I'm not an expert, but other posts I have read seem to suggest that because you are getting misfires across more than one cylinder, it's probably something like your ignition coil, distributor, etc. !
Motorweek - 1987 Ford Escape Hybrid 26-46 was released on: USA: 20 July 2007
If you're only getting a lean indicator and no other problems you might have a vacuum leak or possibly a problem with the EGR valve. The multiple misfires (assuming P0300 or specific cylinders, P0301 ~ P0306) sound like lack of fuel to the injectors causing misfires, also resulting in O2 sensors "sensing" lean mixtures as a result.