This is because the leukaemic cells in the bone marrow take over at the expense of the cells which produce platelets (megakaryocytes). They also affect the production of red blood cells (erythrocytes) leading to anaemia. The first signs of Acute Myeloid Leukaemia in the blood are a low platelet count and a degree of anaemia along with abnormally immature white blood cells from the granulocyte (myeloid) line. The white blood count is not necessarily high.
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