Zack Johnson of The Big Bang Theory is portrayed by actor Brian Smith. Honestly, he isn't a huge part of the series, simply being an on-and-off boyfriend of Pennies. However, he's always funny when he's on!
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The Big Bang Theory episode where Sheldon Cooper plays the theremin is entitled The Bus Pants Utilization.
Melissa Rauch plays Howard's wife on The Big Bang Theory.
Carol Ann Susi plays Howard's mom on The Big Bang Theory, tho she is never seen. We only hear her voice.
Johnny Galecki
Siri was played by Becky O'Donohue.