indiscipline
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Yes, the prefix in the word discipline is "dis-." In linguistics, a prefix is an affix which is placed before the stem of a word. In this case, "dis-" is a prefix that indicates negation or reversal, as in words like "dislike" or "disagree."
Hypo is the opposite of the prefix hyper.
The prefix un- makes the word "unsuitable."
The true opposite of prefix is no prefix.But, as a prefix means something added at the start of a word. the generally understood opposite is suffix - which is something added to the end of a word.
The opposite is impatient.