Since an appetizer comes at the beginning of a meal, whatever comes last would be the opposite: it could be an after dinner drink or dessert. Or another way to look at it would be that the opposite would be something to settle your stomach after you are all done eating. A digestif is an alcoholic drink served at the end that is meant to do just that.
Cocktail aperitif
An aperitif is a before dinner drink. Sake is rice wine from Japan. Sake does, however, make an excellent aperitif.
the best alternative aperitif for sherry
Aperitif for Destruction was created on 2005-05-24.
The cast of Aperitif - 2012 includes: Jim Dandee as Husband Christine Koesler as Wife
It a drink (most of the time an alcoholic one) taken before to eat
it is an aperitif
kir
Arak has an anise flavor.
meze
Ouzo is a Greek aperitif
Aperitif is an alcoholic drink, not a wine, that is served with an appetizer, before the main course. The origin is unknown, but the Italians started using aperitifs in the 18th century after the Egyptians had used it.