The Strongest Weapon is KAMEHAMEHA WAVE its an unrealese weapon XD believe it 1 hit.
the supergun.
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In Damage, Fenrir is the strongest, but in overall, Ultima Weapon is unbeatable.
actually it is the ribauldequin a sick machine gun u keep tapping
EA
Depends on the exact weapon
Omega weapon is the strongest of all the weapon monsters I believe.
Super strong weapon poison is the strongest (P++). It is made with nightshade and poison ivy in a vial of cocnut milk using the herblore skill.
Emerald Weapon
It depends on your class. Some classes use unstable and others use stable. It also depends on enhancements. So pretty much there is no 'strongest' weapon.
the omega weapon ( the final upgrade for all of lightning's weapons )