Can a transwoman have a baby if she receives a donor womb and ovaries etc?
Answer:It is possible, but at the moment it has a very very low chance of success with presentday technology.Answer:To date, there has only been one case of a mostly successful uterus transplant, the uterus was healthy and functional for 6 months. The uterus is a very delicate organ, and is usually rejected by the recipient's body. Rejection is caused by the immune system, detecting damage to the body (the surgical incisions), and looking for a culprit (usually foreign organisms such as bacteria or virus). The immune system finds the transplanted organs, but does not recognize it as belonging there due to differences in the cellular structure between every individual. So the immune system attacks the transplanted organ, killing it. Typically immuno-suppressants are administered to organ recipients to prevent the immune system from attacking it. But without the immune system some form of disease can set in at the incisions destroying the transplanted organ. Because the uterus is connected to the vaginal canal which is open to the outside of the body, the risk of infection is increased 1000 fold over other transplants.In order to transplant a uterus successfully, we have to simultaneously prevent the immune system from attacking it, AND not suppress the immune system, so it can fight infections. One of the present possible ways to do this, is a relatively new technique called microchimerism.Of course transplanting a uterus is not much use without fallopian tubes and ovaries. And THAT'S where things get exciting. Stem cells (created by chemically treating tissue samples from the patient) when injected into a sterilized ovary, create new egg cells. Thus a successful transplant of uterus fallopian tubes, and ovaries into a TS would mean a MtF TS could not only carry a child for the first time, but would be that child's biological mother to boot!The problem lies in donor organs. Micro-chimerism requires months to set in. Donor organs, especially fragile ones such as the uterus have a very limited lifespan outside the body. Thus postmortem donors is out of the question. The best solution is getting these organs donated by FtMs. Unfortunately MtFs outnumber FtMs 3 to 1.