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A. Thrombocytosis is the presence of high platelet counts in the blood, and can be either reactive or primary (also termed essential and caused by a myeloproliferative disease). Increase platelet counts can be due to a number of disease processes:
a. Essential (primary) * Essential thrombocytosis (a form of myeloproliferative disease * Other myeloproliferative disorders such as chronic myelogenous leukemia, polycythemia vera, myelofibrosis b. Reactive (secondary) * Inflammation * Surgery (which leads to an inflammatory state) * Hyposplenism (decreased breakdown due to decreased function of the spleen) * Hemorrhage and/or iron deficiency
Platelets are made in bone marrow, the tissue located inside of bones. Abnormally high platelet production may occur independently, for reasons that are not known (primary thrombocythemia), or as a symptom of another condition (secondary thrombocytosis).
Causes of high platelets in primary thrombocythemia-In this condition, the bone marrow makes too many platelets. This condition may be inherited. Causes of high platelets in secondary thrombocytosis-Thrombocytosis is the occurrence of high platelets as a symptom of another condition. A wide range of diseases and conditions may cause high platelets including:- Anemia (low red blood cell count)
- Blood loss
- Cancer
- Chemotherapy
- Chronic myelogenous leukemia (type of cancer that develops in the bone marrow, the soft tissue inside bones that helps form blood cells)
- Infection
- Inflammatory disorders such as Kawasaki disease (rare childhood disease that involves inflammation of the blood vessels)
- Myelodysplasia (group of conditions in which the blood cells are abnormal in development or function)
- Myelofibrosis (disorder that results in scar tissue in the bone marrow)
- Polycythemia vera (rare bone marrow disorder causing excessive production of blood cells)
- Reaction to certain medications, including steroids
- Splenectomy (surgical removal of the spleen)
In many cases, there is no effect. In some cases it can cause abnormal clotting resulting a heart attack or a stroke. But there are causes associated with it including anemia, infection or cancer.
A few reasons a persons platelet count is high are spleen removal, infection, cancer, and rheumatoid Arthritis. In order to be sure what is causing the high platelet count, one should see their personal doctor.
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Low platelet count?
platelet count
In a Hematology test what is PLT for?
In a hematology test, PLT stands for platelet count. Platelets are small cell fragments in the blood that help with clotting and preventing excessive bleeding. Abnormal platelet counts can indicate various medical conditions such as thrombocytopenia (low platelet count) or thrombocytosis (high platelet count).
What is consider a high platelet count?
A normal platelet count in a healthy individual is between 150,000 and 450,000 per microliter. Ninety-five percent of healthy people will have platelet counts in this range.
How do platelet clumps affect the WBC and platelet counts?
If the platelet clumps are large enough, an automated blood analyzer may mistake them for WBCs, causing a falsely high WBC count. The platelet count will be decreased if there is a lot of clumping.
What is the Platelet Count Test?
What is the Platelet Count Test?
Does splenectomy cause a high platelet count?
Yes, My platelet count was 421 thousand before my splenectomy. One week after removal it was at 2.1 million. Two weeks after my platelet count was at 2.4. My doctors are hoping that it will come down on it's own, but as it looks right now I will have to be on medication to reduce my platelet count. They are expecting it to always be at an elevated level, but they did not expect such high numbers.
What is the significance of a low platelet count?
A low platelet count generally puts an individual at high risk of bleeding, or hemorrhage. The underlying cause of a low platelet count could be several diseases ranging from a something benign to HIV or leukemia.
What causes high Platelet count?
Having a high platelet count is called thrombocytosis. This can be caused by cancer, anemia, rheumatoid arthritis, tuberculosis, and use of birth control pills.
What are some of the potential diagnoses when a 4 olds person has a high platelet count approximately 600 000?
This case had a unknown fever for 7 days and then have be well , but now he have a high platelet count about 613 000.
Failure to gain weight high wbc high platelet count what could this mean?
it means you have a high metabolisim
Is 52000 platelet count normal in dengue fever?
Is a platelet count of 134 with protein in urine normal
What is the platelet count for dengue patient?
When the platelet count falls to less than 100,000mm3
