You can use any letters since it's just like variables in math. They don't really mean anything but you can substitute them to shorten things and to stand for expressions. However, the first letters of the alphabet are often used according to the order they are normally arranged. For example: abb acc ddeeff (for Pindaric odes)
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The most common "silent letters" (they influence pronunciation of other vowels) are the letters E that follow a vowel and a consonant (e.g. date, bite, dote, cute). A pair of consonants GH is silent in words such as fight, height (also silent E), and fought.
Here are some other silent letter words (see related questions):
Silent A : beat, heat, and other AI/EA/OA pairs: aisle, team, spread, heaven, boat, cocoa
Silent B : (MB and BT words) dumb, thumb, tomb, debt, doubt, subtle
Silent C : indict, brick, black (CK pair), scene, science, yacht (silent CH)
Silent D : badge, fudge, Wednesday
Silent E (see above) also :giraffe, pairs such as pie, floe, blue
Silent F : only double FF
Silent G (see above, with H) also: gnat, gnome, sign, campaign, foreign, diaphragm, design
Silent H (see above, with G in high, sigh, weigh, sleigh) also: ghost, rhyme, rhombus, rhododendron, scheme;
what, where, wheat and other WH words, and "lost" H sounds in hour and honor
Silent I : AI words such as aim, laid, pail, pain; EI/IE pairs in believe, receive; UI in juice, sluice
Silent J : (none?)
Silent K : KN words such as knife, knight, knee, knowledge
Silent L : calf, half, could, would, should, salmon; AW sound in walk, talk, solder.
(* the L has a different sound in calm, palm, yolk, but is not silent)
Silent M : mnemonics
Silent N : MN pairs, such as autumn, condemn, solemn, column, hymn
Silent O : EO pairs such as people, jeopardy, leopard
Silent P (not including PH which has an F sound): pneumonia, ptomaine, pteradactyl, raspberry, receipt, psalm, psychic, psychology, and pseudonym.
Silent Q : (none?)
Silent R : February (some dialects)
Silent S : island, aisle
Silent T : castle, mortgage, listen, kitchen, soften, tsar, tsunami, whistle, and Christmas;
also CH pairs in watch, stitch, clutch, and words from French: depot, potpourri, Ballet
Silent U : not counting the QU words like squash, squeeze; there is queue (pronounced "Q"), and also vowel pairs like guess, gauge, laugh, guide, build, guild, buoyant, league, plague (silent UE)
Silent V: (none?)
Silent W : sword, two, who, answer, and OW pairs, bow, flow, window, shadow
Silent X : (none -- makes Z sound leading syllables)
Silent Y : ending as with E, in vowel pairs: bay, day, pay, clay, obey, key
Silent Z : only double ZZ
The letter "n" is not pronounced, therefore, it is the silent letter in the word "hymn".
There are no individual silent letters, they only become silent when they form part of a word, such as the letter 'p' in Psychotic and the letter 'u' in colour.
Many words (for example, "example") have a silent "e" at the end.
Weigh has silent "g" and "h".
Doubt has a silent "b".
Afghanistan has a silent "h".
It is y because when you say the word hymn it doesn't pronounce the y.
Silent consonants are words that are spelled with silent letters. Example: Knife - the k is silent - and it is pronounced "nife" but is spelled knife
The letters b and e are silent in subtle.
There are no silent letters, all letters are sounded.
P + L are the silent letters. The word is pronounced like "Sam"
H is the silent letter