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No. Bupropion (aka Wellbutrin) is known as an atypical antidepressant in that it prevents the reuptake of serotonin, norepinephrine, and dopamine (to a lesser extent). Typical tricyclic antidepressants only block reuptake of serotonin and norepinephrine. It's unique dopamine reuptake inhibition capability allows it to be used to treat nicotine addiction (marketed as Zyban) and, to some extent, attention deficit disorder. Furthermore, it lacks the classic three ring chemical structure of tricyclic antidepressants (TCAs).

Here are a list of some common TCAs:

imipramine (tofranil)

amitriptyline (Elavil/Endep)

doxepin (adapin)

nortrypyline (Pamelor), etc

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Q: Is bupropion a tricyclic antidepressant
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