VoiceOver is controlled from the Seeing section of Universal Access in System preferences. The default keyboard shortcut to toggle VoiceOver on or off are the three keys Command (cmd), Fn, and F5.
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The VoiceOver feature is controlled from the Seeing section of the Universal Access System Preference. The keyboard shortcut to toggle the feature on and off is the Command key, Function 5. Some Mac keyboards have a separate Fn key so you will need the three keys: Cmd, Fn, F5.
To toggle VoiceOver off/on press the Command key and Function (fn) F5. VoiceOver settings can be found in System Preferences in the Universal Access section.