It means that when people get into trouble, for example financial trouble, they may be "backed into a corner" and feel forced to do things they wouldn't normally do in terms of survival.
For example, suppose that you get lost in the woods. After a few days without food, you become desperate for a meal, and so you may find yourself eating plants, bugs, animals, fungus, etc. that you wouldn't normally eat just to survive. This portrays the meaning of the phrase "desperate times call for desperate measures" - the desperate time, or desperate situation, is that you are stuck in a forest without any normal food or means of obtaining such food; the desperate measure is the action plan you follow, namely, to eat anything that is edible until you can afford to eat normally again (i.e., when you find your way out of the woods).
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When people say 'desperate times calls for desperate measures' they mean that the situation has become so serious that they are willing to resort to unorthodox solutions. For example, if you have no money and the bills are due, you may have to mow lawns.
Being desperate is not a disease!!! This among many other things like being hungry proves how humane or normal you are.
The solution to facing anciety in any given period is THE WORD OF GOD.
But assides that there are somethings you need to engage:
Calming your mind,; I suggest meditation 🧘♂️
Praying
Talk to people to take your mind of it.
Desperation can lead to suicide if not treated, just as hunger could lead to death.
I suggest you watch the video below. Especially if you're a Christian who needs real solutions.
youtu.be/kmnRNNoxkRA
No one knows who first said this - it is just a proverb that has passed down to modern times.
Benet Wilson
It may be so old a saying that you won't be able to find an original attribution. To go a bit older than 1964: according to the Oxford dictionary in quotations, on the 6th November 1605, Guy Fawkes is reputed to have said "The desperate disease requires a dangerous remedy"... which is very similar to "extremis malis extrema remedia". But it does not credit this as the original source.
He said Fascinating a total of 49 times in the original series.
A lot of times. Really a lot of times.