Can you take aspirin and tylenol 3 together?

Answer 1

You should not mix Acetaminophen (Tylenol) and Acetylsalicylic acid (Aspirin). The reason for this is long term renal (kidney) damage. What happens in the Tylenol induces the formation of free oxide radicals which damage tissues (especially the kidneys and liver). This is normally not an issue at low Tylenol doses.

However, when you add Aspirin to the mix, the free oxide radicals become an issue. Aspirin is a Cyclooxygenase inhibitor (COX), which decreases prostaglandin (PGE 2) synthesis. Prostaglandins are responsible for vasodilatation of the renal afferent arterioles. If you are on Aspirin the renal afferent arterioles are vasoconstricted and subsequently renal blood flow is decreased. When renal blood flow is compromised your kidney is less able to deal with the free oxide radicals produced by Tylenol.

So what happens?

The free oxide radicals damage the renal medulla (which may slough off) or lose the ability to concentrate urine due to damage to the most notably the thick ascending limb of the nephron. This is called Analgesic Nephropathy.

Having said this, the damage is caused by long term mixing of Tylenol and Aspirin, so having mixed the two in the past once five years ago is not going to compromise your kidneys. Just make sure to avoid the mistake in the future, and pass on this information (there are way too many sources providing incorrect information on this subject).

If you're having pain that bad, maybe your doctor can prescribe something stronger or more effective. It's very important not to exceed the recommended daily dose of either medication. Like prescription medications, there are side effects to medications that you can buy over the counter. When you have questions about medications, the best person to ask is a pharmacist. You can call any drugstore and speak to one, you don't have to be a customer.

Yes you can take both together (called polypharmacy) There used to be an over the counter med called Vanqish. It had aspirin/acetaminophen (TYLENOL) and caffeine. The Tylenol compliments the aspirin and the caffeine helps aspirin work better. BUT don't take high doses of each--take like 325 mg. Tylenol and 325 mg aspirin. If aspirin bothers your stomach, buy coated aspirin, called enteric aspirin. It dissolves in your intestine instead of your stomach. Generic enteric coated aspirin from a place like Wal*Mart is inexpensive. Also save your money and buy generic Tylenol (acetaminophen). Long term use (within reason) should not be a problem.

Do not use Tylenol (acetaminophen) with any other products containing acetaminophen. You can exceed daily recommended limits and cause liver damage. Read all labels carefully (cough syrup, etc.).

Advice from a US licensed pharmacist is that it is safe to take acetaminophen and aspirin together as long as you follow the recommended dosages of either and have no Allergies to either or conditions that would preclude your taking of either of these medications. As above, do not use acetaminophen with any other products containing acetaminophen.

Apparently so, since the active ingredient in Tylenol, acetaminophen, is used in combination with aspirin, in Anacin Advanced (250 mg acetaminophen, 250 mg aspirin and 65 mg caffeine.)

Answer 2

You can indeed take both of these medications at the same time, and in fact your doctor may recommend that you do so. These drugs do not exhibit any inherent, dangerous interaction with each other, and have been in the field for a long time, so no new findings are likely or anticipated.

However, as toxicity is always a function of dosage, any time you take any active medication, you need to be aware of how much you take, and what other medications you're taking that act in the same manner. ibuprofen and Aspirin (acetylsalicylic acid) belong to the group of drugs called NSAIDs - Non-Steroidal Anti-Inflammatory Drugs. They work in a very similar but not identical way. Acetaminophen is not considered an NSAID and is thought to work in the brain rather than peripherally. They are gastrointestinal irritants (APAP, the least irritating, also doesn't perform as well as an anti-inflammatory). They work as pain relievers by inhibiting prostaglandin synthesis. And, even though these drugs do not specifically interact with each other, unsupervised or self-medication has the risk of overdosing, if the patient takes very high doses or two or three of these meds concurrently.

The makers of Tylenol (APAP) specifically do not recommend the patient mixing these drugs without medical supervision. The reason for this is, while the drugs can themselves be safely used concurrently, dosage and over-dosage is always a concern. Understandably, they are worried about accidental overdose resulting from ignorance of the contents of all the medications their customers can take, and they've opted for the most conservative if not the most medically effective course in issuing this warning.

It is further observed that many over the counter and prescription products contain these medications. For instance, Tylenol is the brand name for APAP, so of course it'll contain it. Vicodin, a prescription painkiller, also contains APAP. And so on. The wise patient will keep a sharp eye on this when they use over the counter remedies, and will tell their doctor what they've taken, be it prescription, OTC or homeopathic/natural/herbal medication, so that the caregiver can make a clear, informed decision about further medication. It's generally accepted that the more a patient knows about their condition and medication, the better it is for everyone.

Keep in mind it is important to take the appropriate dosage. Overdosing can lead to drug toxicity.

Answer 3

i believe so , i read that you can take them together just don't make an habit of it . Also both of these medicine's are found in goody's powders so i think Its safe to take it together. also i took both medicine's together i found no harm done i took 1 gram Tylenol 2 500 mg pills and 470 mg aspirin found no harmful effects . be careful with your weight though. If you weigh 120 under i would do 1 500 mg Tylenol and 250 - 300 mg aspirin. I'm not an medical professional so please do not rely on my info but I'm pretty sure your doc will give you around the same numbers. also if you weigh more than 130 you probablycan take 2 500 mg pills Tylenol and 300- 350 mg aspirin . i strongly recommend asking an medical professional though. hope this helps.

Answer 4

You can, but I'm not sure why you would want to. They produce nearly identical therapeutic effects. You should be aware that taking these two classes of medications together increase your chance of bleeding, ulcers, and gastritis. There is also an increase in chances for kidney damage.

Answer 5

This link has some basic info on taking aspirin together with motrin http://www.kidneynotes.com/2006/09/fda-warning-on-taking-aspirin-and.html

Answer 6

I've gotten away with it for many years and my bloodwork always passes fine.

Answer 7

Definitely.