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toxoid

(tŏk'soid') pronunciation

A substance that has been treated to destroy its toxic properties but retains the capacity to stimulate production of antitoxins, used in immunization.

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Dental Dictionary: toxoids

n.pl

Toxins that have been treated to destroy their toxic properties but retain their ability to induce antibody production, thus creating an active immunity.

Britannica Concise Encyclopedia: toxoid

Bacterial toxin that has been made inactive but can still combine with or stimulate formation of antibodies. In many bacterial diseases, the bacteria produce a toxin that causes the disease manifestations. Heating the toxin or treating it chemically converts it into a harmless toxoid that can be injected into a human or a nonhuman animal to confer immunity from subsequent infection. The vaccines for tetanus and diphtheria are toxoids.

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Sports Science and Medicine: toxoid

Toxin that has had its poisonous element removed, but which retains its ability to act as an antigen and stimulate the production of antibodies against the actual toxin.

Columbia Encyclopedia: toxoid,

protein toxin treated by heat or chemicals so that its poisonous property is destroyed but its capacity to stimulate the formation of toxin antibodies, or antitoxins, remains. Because toxoids can be given in large quantities with no risk of tissue damage, they have superseded the highly poisonous toxins as immunizing agents against such diseases as diphtheria and tetanus.

Veterinary Dictionary: toxoid

A toxin treated by heat or chemical agent to destroy its deleterious properties without destroying its antigenicity. Most of the clostridial diseases, e.g. tetanus, are controlled by vaccination with toxoids.

Wikipedia: toxoid

A toxoid is a bacterial toxin whose toxicity has been weakened or suppressed either by chemical (formalin) or heat treatment, while other properties, typically immunogenicity, are maintained. Toxoids are used in vaccines as they induce an immune response to the original toxin or increase the response to another antigen. For example, the tetanus toxoid is derived from the tetanospasmin produced by Clostridium tetani and causing tetanus. The tetanus toxoid is used by many plasma centers in the United States for the development of plasma rich vaccines.

Vaccination/Vaccine (and Immunization, Inoculation. See also List of vaccine topics and Epidemiology)
Development	Adjuvants • Cancer vaccines • DNA vaccination • HIV • Live vector vaccine • Models • Timeline • Trial
Administration	ACIP • GAVI • VAERS • Vaccine court • Vaccine injury • Policy • Schedule • VSD
Live vaccines	Anthrax • BCG • Flu • MMR • MMRV • Polio(OPV) • Smallpox • Varicella
Inactivated/toxoid vaccines	inactivated virus: Flu • HAV • Polio(IPV) •• inactivated bacteria/toxoid: DPwT •• conjugate: Hib • PCV
Other vaccines	subunit: Anthrax • DPaT • HPV •• recombinant DNA: HBV •• other: Anthrax • PPV
Controversy	A-CHAMP • Controversy • NCVIA • Pox party • Safe Minds • Thiomersal

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Copyrights:

		Dictionary. The American Heritage® Dictionary of the English Language, Fourth Edition Copyright © 2007, 2000 by Houghton Mifflin Company. Updated in 2007. Published by Houghton Mifflin Company. All rights reserved. Read more
		Dental Dictionary. Mosby's Dental Dictionary. Copyright © 2004 by Elsevier, Inc. All rights reserved. Read more
		Britannica Concise Encyclopedia. Britannica Concise Encyclopedia. © 2006 Encyclopædia Britannica, Inc. All rights reserved. Read more
		Sports Science and Medicine. The Oxford Dictionary of Sports Science & Medicine. Copyright © Michael Kent 1998, 2006, 2007. All rights reserved. Read more
		Columbia Encyclopedia. The Columbia Electronic Encyclopedia, Sixth Edition Copyright © 2003, Columbia University Press. Licensed from Columbia University Press. All rights reserved. www.cc.columbia.edu/cu/cup/ Read more
		Veterinary Dictionary. Saunders Comprehensive Veterinary Dictionary 3rd Edition. Copyright © 2007 by D.C. Blood, V.P. Studdert and C.C. Gay, Elsevier. All rights reserved. Read more
		Wikipedia. This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Toxoid". Read more

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