Mefloquine is an antiprotozoal, and does not treat bacterial infections. It will not cure chlamydia.

ask gobbers

It is necessary to take primaquine so that it may kill all the gametocytes of p.vivax so that u do not get resistant strains of malaria parasite which is much more dangerous.

Malirid http://www.4nrx.com/infection/malirid-primaquine.html

When your fever has responded to antimalarial drugs, you are taken as cured of malaria. Primaquine removes the parasite from your liver, but then the parasite is not generally removed from liver, when you are resident of the endemic area. If you are from malaria free area or have got falciparum infection, then primaquine course will cure you of malaria.