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Assuming glucose-6-phosphate is in equilibrium with glucose and phosphate, the equilibrium concentration of glucose-6-phosphate would also be 5mM. This is based on the principle of mass action and the equilibrium constant of the reaction between glucose, phosphate, and glucose-6-phosphate.

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Glucose is the substrate that is converted into glucose 6-phosphate by the enzyme hexokinase. Hexokinase catalyzes the phosphorylation of glucose to glucose 6-phosphate in the first step of glycolysis.

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glucose-6-phosphate . . . fructose-6-phosphate

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Hexokinase catalyzes the phosphorylation of glucose to glucose-6-phosphate using ATP as a phosphate donor. This reaction is the first step in glycolysis and plays a crucial role in glucose metabolism in cells.

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All of these enzymes are necessary in the breakdown of glycogen into glucose-6-phosphate molecules.

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Glucose 6 phosphate is regenerated at the end of oxidative phase of pentose phosphate pathway- how it happens explain

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pentose phosphate pathway, glycogenesis, and glycolysis

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The conversion of glucose to glucose 6-phosphate catalyzed by hexokinase/glucokinase is an irreversible reaction that traps glucose within the cell. This process consumes one molecule of ATP and requires Mg2+ as a cofactor. Hexokinase has a high affinity for glucose and is present in most tissues, while glucokinase is found primarily in the liver and pancreas with a lower affinity for glucose.

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The conversion of glycogen to glucose-1-phosphate is the first step in glycogen breakdown, also known as glycogenolysis. This process is catalyzed by the enzyme glycogen phosphorylase, which cleaves off a glucose molecule from the glycogen polymer. Glucose-1-phosphate is then further converted to glucose-6-phosphate for energy production.

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Glucose is converted into Glucose 6 phosphate. One ATP molecule is used.

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Glucose-6-Phosphate to Fructose-6-Phosphate. reversible. Phosphogluctose isomerase.

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The first reaction in glycolysis is the phosphorylation of glucose to glucose-6-phosphate by the enzyme hexokinase. This reaction involves the transfer of a phosphate group from ATP to glucose, requiring energy for activation.

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Glucose-6-phosphate dehydrogenase catalyzes the first step of the pentose phosphate pathway by converting glucose-6-phosphate to 6-phosphoglucono-δ-lactone, producing NADPH in the process. NADPH is essential for reductive biosynthesis and is a key antioxidant in protecting cells from oxidative stress. Deficiency in G6PD can lead to hemolytic anemia due to decreased antioxidant capacity in red blood cells.

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Glycogen is broken down into glucose through a process called glycogenolysis. This process involves the release of glucose molecules from glycogen stores by the enzyme glycogen phosphorylase. These glucose molecules can then be used by the body for energy production.

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Glucose-6-phosphate is important because it serves as an intermediate in glycolysis, providing a starting point for further energy production in the form of ATP. It is also a precursor for the synthesis of nucleotides and amino acids, contributing to various metabolic pathways in the body. Additionally, glucose-6-phosphate plays a crucial role in the pentose phosphate pathway, which generates NADPH for cellular antioxidant defense and biosynthetic processes.

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A coupled reaction is when two reactions are linked, and the energy released from one reaction drives the other. In the conversion of glucose to glucose-6-phosphate, the initial phosphorylation of glucose to form glucose-6-phosphate is coupled with the hydrolysis of ATP to ADP. The energy released from ATP hydrolysis drives the phosphorylation of glucose, making the overall reaction thermodynamically favorable.

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Wayne Warren Miller has written:

'Studies on glucose-6-phosphate dehydrogenase obtained from Vibrio marinus, an obligate marine psychrophile' -- subject(s): Glucose-6-phosphate dehydrogenase

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The steps of glycolysis that are irreversible are the conversion of glucose to glucose-6-phosphate by hexokinase, the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate by phosphofructokinase-1, and the conversion of phosphoenolpyruvate to pyruvate by pyruvate kinase.

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The steps in glycolysis that are irreversible are the conversion of glucose to glucose-6-phosphate by hexokinase, the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate by phosphofructokinase-1, and the conversion of phosphoenolpyruvate to pyruvate by pyruvate kinase.

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Glycolysis is the breakdown of glucose into pyruvate. There are ten reactions in glycolysis. The reactants are glucose, glucose 6-phosphate, fructose 6-phosphate, fructose 1,6 bisphosphate, dihydroxyacetone phosphate, glyceraldehyde 3-phosphate, 1, 3-bisphosphoglycerate, 3-phosphoglycerate, 2-phosphoglycerate, phosphoenolpyruvate and water.

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The formation of glucose 6-phosphate from two molecules of phosphoglyceraldehyde occurs during the second phase of glycolysis, known as the payoff phase. This is achieved through a series of enzymatic reactions that involve the oxidation and rearrangement of the intermediate compounds. Ultimately, the production of glucose 6-phosphate serves as an entry point into further metabolic pathways within the cell.

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Liver glycogen can easily produce glucose by glycogenolysis and that can be used by local cells for respiration.

but as muscle cells lack Glucose-6-phosphate , in muscle glycogen cannot get transferred to glucose and hence cannot be used locally.

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The addition of an inorganic phosphate molecule occurs during the first step of glycolysis, where glucose is phosphorylated to glucose-6-phosphate by the enzyme hexokinase or glucokinase.

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NADPH for fatty acid synthesis is primarily generated through the pentose phosphate pathway (PPP). The enzymes glucose-6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase in the PPP produce NADPH. Another important source of NADPH is the malic enzyme, which converts malate to pyruvate in the mitochondria, generating NADPH in the process.

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Phosphoglucose isomerase is an enzyme that catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate in the glycolysis pathway. This reaction involves the rearrangement of the carbon skeleton of the glucose molecule, resulting in the formation of fructose, which can then continue to be broken down for energy production.

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ATP, citrate, or glucose-6-phosphate

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The acronym G6PD stands for glucose-6-phosphate dehydrogenase. It is sometimes referred to as G6PDH and is an enzyme in the pentose phosphate pathway.

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1 molecule of glucose (6c) -------> glucose -6-phosphate ---->fructose-6-phosphate----->fructose1-6-diphosphate------->2PGAL molecules (3c each ) -------> 2 pyruvic acid molecules ( 3c each ) ------> krebs cycle

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The irreversible reactions in glycolysis are catalyzed by the enzymes hexokinase, phosphofructokinase, and pyruvate kinase. These reactions involve the conversion of glucose to glucose-6-phosphate, fructose-6-phosphate to fructose-1,6-bisphosphate, and phosphoenolpyruvate to pyruvate, respectively.

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Glycogenolysis, breakdown of glycogen, produces glucose-6-phosphate, which in liver is further converted to glucose-1-phosphate that can leave the hepatocytes to the blood. This doesn't happen in muscle cells, so the glucose-6-phosphate is used in glycolysis instead during muscle contraction to produce ATP for myosin.

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Glucose 6 Phosphate is converted into fructose 6 phosphate through the process of glycolysis in preparation for phosphorylation. This is done when cells need carbon or energy for synthesis.

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Hexokinase is regulated by feedback inhibition of Glucose-6-Phosphate. Otherwise, you would make more glucose-6-phosphate than the cell can use at one time. you could also reduce phosphate concentrations needed for making ATP, and set up an osmotic gradient which could lead to swelling of the cells

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The enzyme that converts galactose into glucose 1-phosphate is galactokinase. This enzyme phosphorylates galactose to form galactose 1-phosphate, which can then be converted into glucose 1-phosphate through further metabolic pathways.

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The cleavage of glycogen phosphorylase releases glucose-1-phosphate by breaking the glycosidic bond within glycogen. This glucose-1-phosphate can then be further processed to yield free glucose for energy production.

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Yes, phosphorylation is an important process in glycolysis. During glycolysis, glucose is phosphorylated to form glucose-6-phosphate, which is a key step in the pathway. Phosphorylation helps trap glucose inside the cell and also primes it for further metabolic reactions.

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The source of energy for the first step of glycolysis is the hydrolysis of one molecule of ATP to ADP and inorganic phosphate. This reaction is catalyzed by the enzyme hexokinase and helps to phosphorylate glucose to glucose-6-phosphate.

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The three main steps in glycolysis are: 1) Glucose is phosphorylated to glucose-6-phosphate by hexokinase; 2) Glucose-6-phosphate is isomerized to fructose-6-phosphate by phosphoglucose isomerase; 3) Fructose-6-phosphate is phosphorylated to fructose-1,6-bisphosphate by phosphofructokinase.

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Glycolosis is a metabolic reaction which converts glucose into pyruvate. The first step involves the phopsphate transfer from ATP group to glucose, thus formin glucose 6 phosphate.

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Enzymes involved in the formation of glucose include glucose-6-phosphatase, which converts glucose-6-phosphate to glucose, and phosphoenolpyruvate carboxykinase, which catalyzes the conversion of oxaloacetate to phosphoenolpyruvate in the gluconeogenesis pathway. These enzymes play a crucial role in maintaining blood glucose levels during fasting or starvation.

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Galactose enters glycolysis after it is converted to glucose-6-phosphate in the reaction catalyzed by the enzyme galactokinase. This occurs in the initial steps of glycolysis before glucose-6-phosphate is further metabolized through the glycolytic pathway.

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The irreversible steps of glycolysis are the conversion of glucose to glucose-6-phosphate by hexokinase, and the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate by phosphofructokinase-1. These steps help regulate the flow of glucose through the glycolytic pathway and commit the glucose molecule to further breakdown. By irreversibly trapping glucose in the cell and activating it for energy production, these steps play a crucial role in initiating and driving the overall process of glucose metabolism.

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If an organism lacked hexokinase, it would be unable to phosphorylate glucose to glucose-6-phosphate, which is the first step in glucose metabolism. This would impair the organism's ability to utilize glucose for energy production.

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Glucose is broken down in the first stage of respiration- glycolysis where it is phosphorylated by a molecule of ATP to form 1-6 glucose phosphate. It is then isomerised ti

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The reactant in the first reaction of glycolysis is glucose. Glucose is converted into glucose-6-phosphate by the enzyme hexokinase during the initial step of glycolysis.

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Glucokinase activity is regulated primarily by the concentration of its substrate, glucose. It has a lower affinity for glucose compared to other hexokinases, allowing it to become active only when glucose levels are high. Glucokinase is also subject to allosteric regulation by molecules such as fructose-6-phosphate and mannose-6-phosphate.

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