| ICD-10 | R53. |
|---|---|
| ICD-9 | 780.7 |
| DiseasesDB | 30079 |
| MedlinePlus | 003088 |
| MeSH | D005221 |
The word fatigue is used in everyday living to describe a range of afflictions, varying from a general state of lethargy to a specific work-induced burning sensation within one's muscles. It can be both physical and mental. Physical fatigue is the inability to continue functioning at the level of one's normal abilities[1][2][3]. It is ubiquitous in everyday life, but usually becomes particularly noticeable during heavy exercise. Mental fatigue, on the other hand, rather manifests in somnolence.
Types
Physical fatigue
Physical fatigue or muscle weakness (or "lack of strength") is a direct term for the inability to exert force with ones
muscles to the degree that would be expected given the individual's general physical fitness. A test of strength is often used during a diagnosis of a muscular disorder before the
Mental fatigue
- See also: Somnolence
In addition to physical, fatigue also includes mental fatigue, not necessarily including any muscle fatigue. Such a mental fatigue, in turn, can manifest itself both as somnolence (decreased wakefulness) or just as a general decrease of attention, not necessarily including sleepiness. In any case, this can be dangerous when performing tasks that require constant concentration, such as driving a vehicle. For instance, when a person is sufficiently somnolent, he or she may experience microsleeps. However, objective cognitive testing should be done to differentiate the neurocognitive deficits of brain disease from those attributable to tiredness.
Causes
Fatigue is typically the result of
The sense of fatigue is believed to originate in the reticular activating system of the lower brain. Musculoskeletal structures may have co-evolved with appropriate brain structures so that the complete unit functions together in a constructive and adaptive fashion.[4] The entire systems of muscles, joints, and proprioceptive and kinesthetic functions plus parts of the brain evolve and function together in a unitary way.[5]
Diseases
Temporary fatigue is likely to be e.g. common cold. Chronic fatigue, on the other hand, meaning of six months or more duration, is a symptom of a large number of different diseases on conditions.
- Addison's disease
- AIDS
- Anemia
- Ankylosing Spondylitis
- Anorexia Nervosa
- Anxiety or Panic Disorder
- Arthritis
- ATRT - Brain Cancer
- Autoimmune disease
- B12 Deficiency
- Cancer Syndrome
- Chemical dependency
- Chronic fatigue syndrome (CFS)
- Clinical depression
- Congestive Heart Failure
- Crohn's Disease
- Diabetes
- Epstein-Barr Virus
- Endometriosis
- Fibromyalgia
- Hemochromatosis
- Hepatitis C
- HIV
- Hyperthyroidism/Graves' Disease
- Hyperparathyroidism
- Hypothyroidism/Hashimoto's Thyroiditis
- Idiopathic Hypersomnia
- Lead poisoning
- Leukemia or Lymphoma
- Lupus erythematosus
- Lyme disease
- Interstitial Cystitis
- Mitral valve prolapse/Mitral regurgitation
- Mononucleosis
- Multiple sclerosis
- Muscular Dystrophy
- Myasthenia gravis
- Parkinson's disease
- Pernicious anemia
- Pneumonia
- Post-Cancer Fatigue
- Post-Concussion Syndrome
- Pregnancy
- Primary Biliary Cirrhosis (PBC)
- Reyes Syndrome
- Certain medications, e.g. lithium salts, ciprofloxacin
- Sinusitis
- Sleep deprivation
- Sleep disorders, e.g. insomnia, obstructive sleep apnea, or narcolepsy
- Starvation
- Ulcerative colitis
- Wegener's granulomatosis
- Wilson's Syndrome
Medications
Beta blocker medication causes fatigue, especially after exertion, inducing exercise intolerance. [6]
See also
- Somnolence
- Insomnia
- Combat stress reaction (Battle fatigue)
Malaise - Asthenia
- Paresis
- Debility
- Muscle weakness
- Muscle fatigue
- Infectious mononucleosis
- Celiac disease (gluten sensitivity)
References
- ^ Gandevia SC (1992). "Some central and peripheral factors affecting human motoneuronal output in neuromuscular fatigue". Sports medicine (Auckland, N.Z.) 13 (2): 93-8. PMID 1561512.
- ^ Hagberg M (1981). "Muscular endurance and surface electromyogram in isometric and dynamic exercise". Journal of applied physiology: respiratory, environmental and exercise physiology 51 (1): 1-7. PMID 7263402.
- ^ Hawley JA, Reilly T (1997). "Fatigue revisited". Journal of sports sciences 15 (3): 245-6. PMID 9232549.
- ^ Edelman, Gerald Maurice (1989). The remembered present: a biological theory of consciousness. New York: Basic Books. ISBN 0-465-06910-X.
- ^ Kelso, J. A. Scott (1995). Dynamic patterns: the self-organization of brain and behavior. Cambridge, Mass: MIT Press. ISBN 0-262-61131-7.
- ^ Fatigue caused by medications.
External links
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